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Doctoral Candidate (DC) – CAARE Doctoral Network – 2 Positions

2 PhD positions – within the Doctoral Network CAARE:

DC7 – ‘Impact of continuous downstream process in complex biotherapeutic particles manufacturing’ and

DC8 -‘Scale-up strategies for purification of bionanoparticles’

Applications are invited from suitably qualified candidates for two full-time, 36 months fixed-term positions, as a Doctoral Candidate (DC) on the CAARE Doctoral Network at iBET.

CAARE – “Characterization and Recovery of Bionanoparticles for Vaccine Delivery and Gene Therapy” is a European Doctoral Networks project that deals with the characterization and recovery of bionanoparticles for vaccine delivery and gene therapy. Overall, 14 Doctoral Candidates will be trained at seven institutions in five European countries and will be supported by a network of industrial and academic partners.

At iBET, you will deal with separation processes for bionanoparticles in downstream processing. Your focus will be on scalable, continuous, and integrated processes. You could either develop and apply data-driven modelling or apply advanced analytical tools with the purpose of implementing environment-friendly purification processes or developing and implementing simple scalable purification processes from benchtop to industrial scale. The products to be analysed will be adeno-associated virus or viral-based nanoparticles.

Skills/Qualifications

You have successfully completed your studies in the fields of biotechnology, bio/chemical engineering, or (bio) process engineering.

• Ideally, you have:
• Knowledge of biopharmaceutical process development; process analytical technologies (PAT) and common analytical methods for biopharmaceuticals;
• Previous experience with downstream processing, purification of biopharmaceuticals or bionanoparticles;
• Programming skills and knowledge of machine learning and statistical data evaluation, creation of scientific programme codes using common software packages (MATLAB, Python, R), and mechanistic modelling will be an advantage;
• Good communication skills in English, both written and verbal;
• Ability and commitment to producing scientific outputs for publication in peer-reviewed journals;
• Evidence of the ability to work independently and collaboratively within an international team;
• Willingness to take on responsibility;
• Motivation, and excellent organization skills with strong attention to detail and quality;
• Willingness to travel to attend secondments, training, and academic events.

• Specific Requirements
• At the effective starting date of this contract, applicants must not have been awarded a PhD;
• At the effective starting date of this contract, applicants must not have resided in Portugal for more than 12 months in the 36 months immediately before the appointment;
• Master’s concerning the scientific disciplinary area of relevance obtained in Portugal or the equivalent title obtained abroad (Biotechnology, Bioengineering, Biochemical Engineering);
• An excellent track record of academic achievement.

Apply now with your detailed CV, motivation letter, and degree certificates to Ver o e-mail no click.appcast.io, referring to the job reference in the subject of the email (CAARE2024).
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